3.3 Urinary System
Overview
The urinary system is responsible for cleansing the blood and removing wastes from the body. It also plays a role in regulating pH, blood pressure, and the concentration of electrolytes in the blood. Controlled by the nervous system, the urinary system also stores urine until a convenient time for disposal, then provides the structures for transporting liquid waste from the body, thus maintaining homeostasis.
The Path of Urine
Blood from the heart enters each kidney via the renal artery. The blood is then filtered by the nephrons (the functional units of the kidney), and waste products are removed which forms urine. The filtered blood then leaves the kidneys via the renal veins. The urine is drained from the kidneys into the ureters, which transport the urine to the urinary bladder (Fowler et al., 2013). This is where urine is stored until it is excreted from the body through the urethra.
CrashCourse. (2015, October 12). Urinary system, part 1: Crash Course anatomy & physiology #38 [Video]. You Tube. https://www.youtube.com/watch?v=l128tW1H5a8&ab_channel=CrashCourse
Structures of the Urinary System
Kidneys: Paired organs in the abdomen that are attached to the dorsal wall on either side of the spine. Kidneys are imperative in maintaining homeostasis and contain nephrons that filter the blood. Mammals have two kidneys, but they are shaped differently in different species.
Ureters: Tubes extending from the kidneys to the urinary bladder that are used to transport urine. Each kidney has one ureter.
Urinary bladder: A hollow, muscular organ that collects urine from both ureters and holds it until it is released from the body via the urethra. The size of the bladder depends on the amount of urine in it.
Urethra: A tube that transports urine from the bladder to outside the body.
COMBINING FORM | MEANING | EXAMPLES USED IN VETERINARY MEDICINE |
---|---|---|
cyst/o | urinary bladder | cystocentesis |
nephr/o, ren/o | kidney | nephritis |
ur/o, urin/o | urine, urinary tract | urinalysis |
Common Pathological Conditions of the Urinary System
Cystitis: Inflammation of the urinary bladder
Feline lower urinary tract disease (FLUTD): A common disease in cats; any disorder affecting the bladder or urethra of cats
Urethral obstruction: A condition in which the urethra is blocked, which prevents urination. This is most common in male cats (and male goats) and is also referred to as “blocked cat” in companion animal practice. It is a condition requiring emergency treatment.
VETgirl. (March 3, 2015). Feline urethral obstruction (FUO) | How to unblock a cat | VETgirl veterinary CE videos [Video]. YouTube. https://www.youtube.com/watch?v=x0HsTgPuP14
Kidney failure (Renal failure): Inability of the kidneys to function that occurs when the kidneys lose all, or some, of their ability to produce urine and filter the blood. This can present as an increase or decrease in urination.
Clinical Insight
There is both chronic renal failure (chronic kidney disease) and acute renal failure (acute kidney injury). Generally, the acute condition has a faster onset, whereas the chronic condition develops more slowly over time. An example of acute renal failure would be when a cat eats lilies—these flowers are toxic to cats and very dangerous to their kidneys!
Inappropriate urination: Eliminating urine at the wrong time or in the wrong place (e.g., in cats, urinating outside the litterbox)
Incontinence: The loss of the ability to control the release of urine from the bladder
Urolith: A stone in the urinary tract; also called a calculus
Example
Urinary tract infection (UTI): An infection anywhere in the urinary tract
Clinical Insight
Just like female humans, female dogs are more likely to get UTIs than their male counterparts.
Common Procedures
Cystocentesis: A surgical puncture of the bladder; the direct extraction of urine from the bladder using a needle and syringe
Cystotomy: A surgical incision of the bladder
Nephrectomy: Surgical removal of a kidney
Radiography: An imaging technique used to visualize the inside of an animal
Urinalysis (UA): Analyzing the composition of urine using laboratory tests
Urinalysis
A urinalysis can be performed in a clinic, or a urine sample can be sent to an off-site lab for analysis. The first step of the analysis is the gross examination, in which the urine is examined by the naked eye for observation of the colour, turbidity (transparency), and odour. The second step is a chemical analysis in which drops of urine are placed on a reagent strip (Figure 3.6) to observe the reaction of the substances in the urine. Some of the chemical reactions determine pH, glucose, ketones, and bilirubin levels in the urine. To measure how concentrated the urine is, a drop is placed on a refractometer to check the urine’s specific gravity, which tells us how concentrated or dilute the urine is—an indicator of how well the kidneys are filtering. The last step is a microscopic examination in which the urine is viewed under a microscope. In this step, the urine is viewed at a cellular level and the presence of blood, bacteria, and crystals are observed (Burton & Lalande, 2021). For more laboratory details, see 5.4. Laboratory Terminology.
Urinary catheterization: Placing a catheter (a hollow tube) inside the urethra to collect urine
Urine culture and sensitivity: A diagnostic test used to determine whether bacteria are present in the urine, and if so, which antibiotics they are susceptible to
Acronyms
AKI: acute kidney injury
ARF: acute renal failure
BUN: blood urea nitrogen
CKD: chronic kidney disease
CRF: chronic renal failure
FLUTD: feline lower urinary tract disease
PD: polydipsia
PU: polyuria
UA: urinalysis
USG: urine specific gravity
UTI: urinary tract infection
Clinical Insight
BUN and creatinine are major kidney values that veterinarians evaluate on bloodwork.
Additional Urinary Terms
Anuria: No urine production
Bacteriuria: Bacteria present in the urine
Crystalluria: Crystal formation in the urine
Dysuria: Painful urination
Glucosuria: The presence of glucose in the urine
Hematuria: The presence of blood in the urine
Polydipsia: Excessive or increased drinking or consumption of water
Polyuria: Excessive or increased urine production
Void: To empty urine from the body
Exercise
Attribution
Unless otherwise indicated, material on this page has been adapted from the following resource:
Sturdy, L., & Erickson, S. (2022). The language of medical terminology. Open Education Alberta. https://pressbooks.openeducationalberta.ca/medicalterminology/, licensed under CC BY-NC-SA 4.0
References
Burton, E., & Lalande, A. (2021). Clinical veterinary diagnostic laboratory. University of Minnesota. https://pressbooks.umn.edu/cvdl, licensed under CC BY-NC 4.0
Fowler, S., Roush R., Wise, J., Reeves, N., DeSaix, J., Kuehner, B., Leady, B., Boggs, L., Broverman, S., Byres, D., Marcus, B., Mhlanga, F., Mignone, M., Nash, E., Newton, M., Oliveras, D., Piperberg, J., Reisenauer, A., Rumfelt, L., Belk, M. … Zoubina, E. (2013). Concepts of biology. OpenStax. https://openstax.org/details/books/concepts-biology, licensed under CC BY 4.0
Image Credits
(images are listed in order of appearance)
Keogh, L., Kilroy, D., & Bhattacharjee, S. (2020). The struggle to equilibrate outer and inner milieus: Renal evolution revisited. Annals of Anatomy – Anatomischer Anzeiger, 233, 151610. http://dx.doi.org/10.1016/j.aanat.2020.151610, licensed under CC BY 4.0
Dog Bladder (26990477411) by National Human Genome Research Institute (NHGRI), CC BY 2.0
Urinary bladder stones by mirkosajkov, Pixabay licence
Special urine test during urine analysis by Ajay Kumar Chaurasiya, CC BY-SA 4.0
biological process that results in stable equilibrium
Functional unit of the kidney that filters blood
surgical puncture of the urinary bladder with a needle to remove urine
Inflammation of the kidneys
is a panel of medical tests that includes physical (macroscopic) examination of the urine
blood in the urine
difficulty urinating
an instrument that measures the density of urine compared to pure water via the refractive index.